Michael Wolzt Selected Research

ABIO 0801

1/2009

Double-blind, placebo-controlled, multiple-ascending-dose study on the pharmacodynamics of ABIO-08/01, a new CNS drug with potential anxiolytic activity. 1. EEG mapping, psychometric and tolerability findings.

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Michael Wolzt Research Topics

Disease

15	Insulin Resistance 05/2021 - 04/2006
15	Inflammation (Inflammations) 01/2017 - 09/2002
12	Heart Failure 07/2015 - 02/2003
11	Endotoxemia 07/2013 - 01/2002
11	Type 2 Diabetes Mellitus (MODY) 04/2012 - 11/2006
8	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 06/2011 - 06/2003
7	Stroke (Strokes) 01/2022 - 11/2006
7	Atrial Fibrillation 01/2022 - 03/2003
7	Thrombosis (Thrombus) 07/2016 - 06/2004
7	Cardiovascular Diseases (Cardiovascular Disease) 11/2015 - 09/2005
6	Hemorrhage 01/2021 - 08/2005
6	Body Weight (Weight, Body) 07/2013 - 09/2004
5	Acute Coronary Syndrome 01/2021 - 02/2003
5	Ischemia 01/2018 - 03/2008
5	Hyperoxia 04/2014 - 07/2002
5	Hyperglycemia 09/2013 - 01/2003
4	Neoplasms (Cancer) 01/2020 - 01/2013
4	Chronic Obstructive Pulmonary Disease (COPD) 01/2017 - 10/2008
4	Eye Diseases (Eye Disease) 12/2014 - 01/2010
4	Obesity 12/2008 - 04/2006
4	Myocardial Infarction 07/2007 - 11/2006
3	Wounds and Injuries (Trauma) 01/2022 - 10/2011
3	Peripheral Arterial Disease 01/2019 - 04/2005
3	Coronary Artery Disease (Coronary Atherosclerosis) 12/2018 - 08/2005
3	Diabetes Mellitus 10/2015 - 03/2011
3	Chronic Renal Insufficiency 01/2015 - 01/2012
3	Hypertension (High Blood Pressure) 01/2015 - 09/2006
3	Hyperemia 10/2013 - 11/2003
3	Gestational Diabetes (Gestational Diabetes Mellitus) 04/2011 - 01/2007
3	Hyperinsulinism (Hyperinsulinemia) 05/2007 - 01/2003
3	Weight Loss (Weight Reduction) 03/2007 - 12/2004
3	Vascular Diseases (Vascular Disease) 02/2007 - 02/2003
2	Infections 11/2021 - 10/2021
2	Coronary Disease (Coronary Heart Disease) 01/2020 - 01/2015
2	Vascular System Injuries 12/2017 - 03/2008
2	Proteinuria 01/2015 - 12/2014
2	Leukocytosis (Pleocytosis) 03/2014 - 03/2012
2	Ischemic Stroke 02/2014 - 01/2012
2	Gilbert Disease 09/2013 - 09/2013

Drug/Important Bio-Agent (IBA)

16	Glucose (Dextrose)FDA LinkGeneric 04/2015 - 11/2003
15	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2017 - 12/2004
12	Insulin (Novolin)FDA Link 04/2015 - 01/2003
10	Nitric Oxide Synthase (NO Synthase)IBA 01/2017 - 01/2002
7	LipidsIBA 04/2015 - 01/2007
7	Retinaldehyde (Retinal)IBA 04/2014 - 07/2002
7	AntioxidantsIBA 04/2014 - 09/2002
6	Thrombin FDA Link 07/2016 - 02/2003
6	Ascorbic Acid (Vitamin C)FDA LinkGeneric 12/2014 - 11/2003
6	Escherichia coli endotoxinIBA 07/2013 - 09/2002
6	ximelagatran (Exanta)IBA 04/2012 - 02/2003
6	dimethylarginineIBA 01/2008 - 06/2004
5	AnticoagulantsIBA 10/2021 - 04/2012
5	Vasodilator Agents (Vasodilators)IBA 01/2018 - 09/2002
5	fibrin fragment D (D-dimer)IBA 07/2016 - 07/2006
5	Adenosine Triphosphate (ATP)IBA 04/2012 - 05/2007
5	Nicotinamide PhosphoribosyltransferaseIBA 06/2010 - 04/2006
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2009 - 08/2003
5	C-Reactive ProteinIBA 10/2008 - 12/2004
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2008
4	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2021 - 02/2014
4	TicagrelorIBA 10/2020 - 02/2014
4	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2018 - 09/2002
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2015 - 04/2005
4	CatecholaminesIBA 04/2015 - 01/2002
4	Oxygen (Dioxygen)IBA 03/2014 - 07/2002
4	CreatinineIBA 01/2012 - 08/2005
4	LipopolysaccharidesIBA 01/2010 - 11/2003
4	GhrelinIBA 09/2008 - 01/2003
4	Norepinephrine (Noradrenaline)FDA LinkGeneric 08/2007 - 11/2003
4	Vasoconstrictor AgentsIBA 01/2007 - 11/2003
3	Prasugrel Hydrochloride FDA Link 10/2020 - 02/2014
3	Clopidogrel (Plavix)FDA Link 10/2020 - 02/2014
3	Pharmaceutical PreparationsIBA 01/2019 - 04/2004
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/2017 - 08/2013
3	Interleukin-6 (Interleukin 6)IBA 01/2017 - 10/2008
3	Nonesterified Fatty Acids (NEFA)IBA 04/2015 - 11/2006
3	Proteins (Proteins, Gene)FDA Link 01/2013 - 06/2004
3	melagatranIBA 04/2012 - 10/2003
3	AntithrombinsIBA 04/2012 - 03/2003
3	pro-brain natriuretic peptide (1-76)IBA 08/2011 - 07/2008
3	AdipokinesIBA 06/2010 - 04/2006
3	CholesterolIBA 08/2009 - 03/2007
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2008 - 12/2004
3	Nitroglycerin (Dynamite)FDA LinkGeneric 03/2008 - 09/2002
3	Arginine (L-Arginine)FDA Link 03/2008 - 06/2004
3	Simvastatin (Zocor)FDA LinkGeneric 02/2008 - 11/2004
3	C-PeptideIBA 01/2008 - 06/2003
2	N(4)-oleylcytosine arabinosideIBA 10/2021 - 01/2019
2	EnzymesIBA 05/2021 - 07/2008
2	landiololIBA 12/2019 - 01/2018
2	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 12/2017 - 01/2007
2	P-SelectinIBA 07/2016 - 03/2003
2	ZincIBA 12/2014 - 04/2014
2	Immunosuppressive Agents (Immunosuppressants)IBA 09/2013 - 06/2004
2	BilirubinIBA 09/2013 - 09/2013

Therapy/Procedure

22	Therapeutics 01/2022 - 02/2003
3	Secondary Prevention 12/2018 - 01/2007
3	Endurance Training 02/2012 - 10/2003
2	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 11/2016 - 03/2006
2	Transplantation 09/2013 - 04/2012